A comprehensive software package for the analysis, reconstruction and visualization of three-dimensional nucleic acid structures. 3DNA can be applied to parallel and antiparallel double helices, single-stranded forms, multi-stranded helices and complex tertiary folding motifs found in both DNA and RNA structures. The rebuilding module of 3DNA can be used to generate sequence-dependent atomic structures of nucleic acids, with or without the sugar–phosphate backbone. These structures provide a useful starting point for molecular mechanics and molecular dynamics calculations.

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3DNA classification

3DNA specifications

Software type:
Package
Restrictions to use:
None
Programming languages:
ANSI C
Version:
2.3
Interface:
Command line interface
Operating system:
Unix/Linux, Mac OS, Windows
Computer skills:
Advanced
Stability:
Stable

Publications

  • (Lu et al., 2003) 3DNA: a software package for the analysis, rebuilding and visualization of three‐dimensional nucleic acid structures. Nucleic Acids Research.
    PMID: 12930962

3DNA support

Documentation

Additional informations

Users need to register in the 3DNA forum and then login to see the downloads section.

Credits

Institution(s)

Department of Chemistry and Chemical Biology, Wright-Rieman Laboratories, The State University of New Jersey, Piscataway, NJ, USA

Funding source(s)

This work has been supported by the US Public Health Service under research grant GM20861.

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