Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 29
Release date: Sep 29 2015
Last update date: Aug 9 2018
Access: Public
Diseases: Neoplasms, Ovarian Neoplasms
Dataset link Transformation of Human Fallopian Tube Stem Cells and high grade serous ovarian cancer

Experimental Protocol


FTSCs were immortalized or transformed with retroviral infection of hTERT, SV40 and c-myc and then subcutaneously transplanted into highly immunocompromised NSG (NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ) mice. Total RNA was isolated from FTSC, immortalized FTSC, transformed FTSC, xenografting tumors. For contarol samples, we also use HGSOC and paired normal oviduct samples from 10 independent patients (samples were isolated laser captured microdissection (LCM)). We used Affymetrix chips (HG-U133_Plus_2).

Repositories


GEO

GSE69428

BioProject

PRJNA285476

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Contact


Frank McKeon