Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 11
Release date: Jun 1 2014
Last update date: Mar 3 2017
Access: Public
Diseases: Amyotrophic Lateral Sclerosis, TDP-43 Proteinopathies
Dataset link Loss of nuclear TDP-43 in ALS causes altered expression of splicing machinery and widespread dysregulation of RNA splicing in motor neurons [NSC34]

Experimental Protocol


RNA was extracted from NSC34 motor neuronal cells depleted of TDP-43 by shRNA (n=4), treated with control shGFP (n=4), and treated with control shLuciferase (n=3).

Repositories


GEO

GSE56503

ArrayExpress

E-GEOD-56503

BioProject

PRJNA243564

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Contact


Paul Heath
Paul Roy Heath