Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 16
Release date: Jun 30 2015
Last update date: May 11 2017
Access: Public
Diseases: Cardiovascular Diseases, Heart Defects, Congenital, Nervous System Malformations, CHARGE Syndrome
Dataset link The Chromatin Remodeller CHD7 Lies Upstream of Semaphorin, Slit/Robo and Calcium Handling Pathways during Cardiovascular Development

Experimental Protocol


We performed microarrays on whole hearts dissected from E11.5 and E13.5 embryos, resulting from crossing Chd7fl/+;Mesp1-Cre mice with Chd7fl/fl mice. This ablates Chd7 expression specifically in the mesoderm, from which the heart derives.

Repositories


GEO

GSE59963

BioProject

PRJNA257189

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