Computational protocol: HECTD2 Is Associated with Susceptibility to Mouse and Human Prion Disease

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Protocol publication

[…] PLINK was used for association and permutation testing. The primary analysis was a trend model chi-squared test. Haplotype inference was made with PLINK and Haploview using standard expectation-maximisation algorithms. The haplotype association test was implemented through PLINK. […]

Pipeline specifications

Software tools PLINK, Haploview
Application GWAS
Organisms Mus musculus, Homo sapiens, Bos taurus
Diseases Brain Diseases, Creutzfeldt-Jakob Syndrome, Prion Diseases, Neurodegenerative Diseases