Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 8
Release date: Feb 13 2017
Last update date: Aug 23 2018
Access: Public
Diseases: Adenocarcinoma, Brain Neoplasms, Neoplasms, Pancreatic Neoplasms
Dataset link Therapeutic vulnerabilities of mesenchymal subpopulations of pancreatic cancer cells undergoing anabolic reprogramming [set 1]

Experimental Protocol


Kras mutant pancreatic epithelial cells were cultured under oncogenic stress. Spontaeneous senescence escapers were isolated, expanded and functionally characterized. Four indepedent biological replicates per each of two groups were processed on Affymetrix Mouse 430_2 microarray platform. Resulting CEL files were imported into Gene Pattern software from the Broad Institute, and converted to normalized GCT format using default parameters in module, ExpressionFileCreator. Normalized GCT table format was used for Gene Set Enrichment Analysis (GSEA) using GSEA software provided by the Broad Institute, Cambridge MA.

Repositories


GEO

GSE83752

BioProject

PRJNA326930

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Contact


Giannicola Genovese