|Application:||Gene expression microarray analysis|
|Number of samples:||56|
|Release date:||Dec 1 2007|
|Last update date:||Aug 28 2018|
|Diseases:||Immune System Diseases, Leukemia, Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell|
|Dataset link||CLL in Em-TCL1 mice provides a biologically relevant model to unravel and reverse immune deficiency in human cancer.|
CD4 T cells and CD8 T cells were obtained from spleens of B6C3 and Em-TCL1 transgenic murine model of CLL or from peripheral blood mononuclear cells of previously untreated patients with CLL and healthy individuals (Pubmed ID: 15965501). Gene expression profiling was performed using total RNA and the data were analysed to compare gene expression profile of CLL to healthy within or between the species.