Dataset features

Specifications


Application: RNA-seq analysis, sRNA-seq analysis
Number of samples: 16
Release date: Oct 31 2017
Last update date: Nov 28 2018
Access: Public
Diseases: Amyotrophic Lateral Sclerosis, Nervous System Diseases, Neurodegenerative Diseases
Dataset link FUS mutant human motoneurons transcriptome analysis reveals altered pathways and impairment of microRNA function

Experimental Protocol


High-throughput sequencing of total RNA from human iPSC-derived motoneurons Hb9::GFP-positive (day12), 2 replicates; human iPSC-derived neural cells Hb9::GFP-negative (depleted of motoneurons, day12), 2 replicates; human iPSC-derived motoneurons FUS-WT (day12+7), 3 replicates; human iPSC-derived motoneurons FUS-P525L/P525L mutant (day 12+7), 3 replicates. High-throughput sequencing of small RNA from human iPSC-derived motoneurons FUS-WT (day12+7), 3 replicates; human iPSC-derived motoneurons FUS-P525L/P525L mutant (day 12+7), 3 replicates.

Repositories


GEO

GSE94888

ENA

SRP099660

BioProject

PRJNA374724

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Contact


Alessandro Rosa