Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 4
Release date: Oct 3 2015
Last update date: Aug 23 2018
Access: Public
Diseases: Hypercholesterolemia, Atherosclerosis
Chemicals: Bile Acids and Salts, Cholesterol
Dataset link A diet-sensitive epigenetic pathway links hepatic bile acid metabolism to cholesterol absorption and atherosclerosis

Experimental Protocol


Wild type and Baf60a Liver specific knockout (Baf60a LKO) mice were fed high-fat diet (Research Diets D12492) for 10 weeks. Livers were harvested after overnight starvation for RNA isolation and microarray hybridization using Affymetrix Mouse Genome 430 2.0 Array. Two independent pool RNA samples from WT and Baf60a LKO mouse livers were included in the study.

Repositories


GEO

GSE73709

BioProject

PRJNA297701

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Contact


Zhuoxian Meng