|Application:||Gene expression microarray analysis|
|Number of samples:||4|
|Release date:||Jan 17 2013|
|Last update date:||Oct 29 2018|
|Diseases:||Neoplasms, Colorectal Neoplasms, Tumor Lysis Syndrome|
|Dataset link||Expression data from fibroblasts treated with TGF-Beta|
CCD-Co-18 were seeded at 60% confluence and treated with TGF-β1. Gene expression profiles were measured in duplicate using HG-U133 plus 2.0. We used RMA background correction, quantile normalization and RMA summarization (Gautier et al., 2004). A TGF-β response signature was obtained by selecting genes with limma P-value < 0.05 and at least two fold up-regulation in TGF-β treated fibroblasts.