Computational protocol: The influence of renal function on the association of rs854560 polymorphism of paraoxonase 1 gene with long-term prognosis in patients after myocardial infarction

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Protocol publication

[…] STATISTICA 9.0 software was used for statistical analysis. After testing for distribution with Shapiro–Wilk test, clinical parameters were compared between the genotypes with χ2 or Kruskal–Wallis tests, as appropriate. Survival was compared with log-rank test. Univariate and multivariate analyses for 5-year survival were performed with Cox proportional hazards model. Based on analysis of survival curves and mortality rates, a recessive model of penetrance was assumed. Two-sided p value <0.05 was considered statistically significant. The biostatistical parameters were calculated using ARLEQUIN v.3.0 software. […]

Pipeline specifications

Software tools Statistica, Arlequin
Applications Miscellaneous, Population genetic analysis
Organisms Homo sapiens
Diseases Coronary Artery Disease, Kidney Diseases, Myocardial Infarction, Renal Insufficiency, Chronic