|Application:||Gene expression microarray analysis|
|Number of samples:||4|
|Release date:||Feb 19 2011|
|Last update date:||Aug 23 2018|
|Diseases:||Deficiency Diseases, Muscular Diseases, Muscular Dystrophy, Duchenne|
|Dataset link||Gene expression profiles using microarrays in mdx and mdx/MMP-2-/- mice at 1 and 3 months of age|
Tibialis anterior muscle was isolated from four groups of mice (mdx and mdx/MMP-2-/- mice at 1 and 3 months of age). Total RNA was purified and prepared for hybridization to Affymetrix Mouse Genome 430 2.0 arrays (Affymetrix Inc., Santa Clara, CA, USA) using Affymetrix reagents and protocols. The mRNA levels of differentially expressed genes from gene chip analysis were confirmed by quantitative real-time PCR assay.