|Application:||Gene expression microarray analysis|
|Number of samples:||16|
|Release date:||Jan 19 2016|
|Last update date:||Jun 14 2018|
|Diseases:||Heart Failure, Hypertension, Neoplasms, Second Primary, Myocardial Ischemia|
|Dataset link||Mitochondrial functional aberrations in a mouse model of non-ischemic heart failure|
Twelve week-old C57BL6 male mice were randomly assigned to 4 groups: 1. Control, 2. L-NAME treatment, 3. AngII treatment, 4. L-NAME+AngII treatment.L-NAME (0.3 mg/ml with 1% NaCl) was administered in drinking water. AngII (0.7 mg/kg/day) was administered via subcutaneous micro-osmotic pumps. L-NAME and AngII were administered to mice for 5 weeks and 4 weeks in combination to induce HF or alone to study the effects of the individual agents.