Dataset features

Specifications


Application: RNA-seq analysis
Number of samples: 30
Release date: Dec 6 2017
Last update date: Oct 24 2018
Access: Public
Dataset link HDAC inhibitor SAHA reverses inflammatory gene expression in diabetic endothelial cells

Experimental Protocol


Human aortic endothelial cells from a diabetic and non-diabetic individual were stimulated with DMSO (control), SAHA (2 μM, HDAC inhibitor) or C646 (10 μM, EP300 inhibitor) for 12 hours, or EP300 siRNA or non-target siRNA (control) for 4 hours, followed by 48 hours in fresh media. Study performed in triplicate.

Repositories


GEO

GSE77108

ENA

SRP068733

BioProject

PRJNA309443

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