Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 6
Release date: Feb 28 2012
Last update date: Aug 23 2018
Access: Public
Diseases: Hamartoma Syndrome, Multiple, Prostatic Neoplasms
Dataset link Pten loss and RAS/MAPK activation cooperate to promote EMT and prostate cancer metastasis initiated from stem/progenitor cells

Experimental Protocol


Murine mutants with prostate specific loss of Pten and K-ras activation (K-rasG12D) under regulation of the probasin promoter developed high grade, invasive prostate cancer. RNA was extracted from dissected prostate lobes from individual mutants with pathology thought to closely mimic human disease. Prostate tissue was subject to RNA extraction and hybridization on Affymetrix cDNA microarrays.

Repositories


GEO

GSE34839

ArrayExpress

E-GEOD-34839

BioProject

PRJNA150213

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Contact


Linh Tran
Linh My Tran