Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 30
Release date: Jan 19 2017
Last update date: Jul 26 2018
Access: Public
Diseases: Prostatic Neoplasms
Chemicals: Selenium
Dataset link A short-term intervention with selenium affects expression of genes implicated in the epithelial-to-mesenchymal transition in the prostate

Experimental Protocol


For this randomized, placebo-controlled intervention trial, 23 men were randomly assigned to take 300 µg selenized yeast per day (n=12) or placebo (non-selenized yeast, n=11) during a median intervention period of 35 (interquartile range: 31-35) days. Prostate specimens, collected from the transition zone before and after intervention, of 15 participants (n=8 selenium, n=7 placebo) were available for analyses using Affymetrix GeneChip Human 1.0 ST Arrays. This study is registered at clinicaltrials.gov with identifier NCT00446901.

Repositories


GEO

GSE77959

BioProject

PRJNA312203

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Contact


Guido Hooiveld

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