Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 30
Release date: Feb 29 2016
Last update date: Aug 9 2018
Access: Public
Diseases: Lupus Erythematosus, Systemic, Lupus Nephritis, Renal Insufficiency
Genes: IFNA1
Dataset link Global gene expression profiles in whole blood total RNA from patients with lupus nephritis, before and after initiation of therapy

Experimental Protocol


Global gene expression studies were performed in serial whole blood samples from SLE patients with a renal BILAG A prior to, 3 months, and 6 months after initiation of conventional immunosuppressive therapy (induction with high-dose corticosteroids, IV cyclophosphamide or oral mycophenolate during the first 3 months, followed by maintenance with moderate- to low-dose corticosteroids, azathioprine or mycophenolate). The expression of IFN-induced genes was analyzed, in comparison to global and renal indices of disease activity.

Repositories


GEO

GSE72747

ArrayExpress

E-GEOD-72747

BioProject

PRJNA294806

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Contact


Bernard Lauwerys
Bernard Robert Lauwerys

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