|Number of samples:||79|
|Release date:||Aug 17 2017|
|Last update date:||Nov 21 2018|
|Genes:||SOX2, TBX1, TBX6|
|Dataset link||Antagonistic activities of Sox2 and Brachyury control the fate choice of neuro-mesodermal progenitors|
Bulk transcriptomes (RNA-Seq) and chromatin accessibility (ATAC-Seq) from T/Sox2 expressing subpopulations isolated during trunk development from wildtype and T knock-out mouse embryos. Data is supplemented by Fluidigm single-cell RNA-Seq for T/Sox2 co-expressing cells from wildtype embryos and a bulk RNA-Seq comparison of wildtype and Tbx6 knock-out mouse embryos. ChIP-Seq for T, Sox2, Tbx6 and beta-catenin has been performed with chromatin from in vitro differentiated neuromesodermal progenitors and presomitic mesoderm.