Dataset features

Specifications


Application: RNA-seq analysis
Number of samples: 36
Release date: Jan 3 2018
Last update date: Nov 21 2018
Access: Public
Diseases: Adenocarcinoma, Neoplasms, Pancreatic Neoplasms
Dataset link Adaptive and reversible resistance to Kras inhibition in pancreatic cancer cells

Experimental Protocol


6 DOX-inducible shKras-expressing clones derived from 3 parental pancreatic tumor cell lines (A, B, and D; 2 clones per cell line) were treated with doxycycline (DOX) to induce Kras knockdown. One control DOX-inducible shLuc-expressing line was used as a control. RNA-sequencing was performed on long-term DOX-treated (LT DOX) or untreated (No DOX) cells. Technical replicates for specific samples are noted.

Repositories


GEO

GSE95478

ENA

SRP100830

BioProject

PRJNA377242

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