|Number of samples:||36|
|Release date:||Jan 3 2018|
|Last update date:||Nov 21 2018|
|Diseases:||Adenocarcinoma, Neoplasms, Pancreatic Neoplasms|
|Dataset link||Adaptive and reversible resistance to Kras inhibition in pancreatic cancer cells|
6 DOX-inducible shKras-expressing clones derived from 3 parental pancreatic tumor cell lines (A, B, and D; 2 clones per cell line) were treated with doxycycline (DOX) to induce Kras knockdown. One control DOX-inducible shLuc-expressing line was used as a control. RNA-sequencing was performed on long-term DOX-treated (LT DOX) or untreated (No DOX) cells. Technical replicates for specific samples are noted.