|Number of samples:||17|
|Release date:||Jul 8 2014|
|Last update date:||Oct 17 2018|
|Taxon:||Homo sapiens, Mus musculus|
|Dataset link||High-resolution mapping of chromatin packaging in mouse embryonic stem cells and sperm|
We use Micrococcal Nuclease (MNase) to map chromatin structure in mouse ES cells and sperm. Specifically, we generate paired-end deep-sequencing libraries that are able to distinguish DNA digestion products by size, thus allowing us to simultaneously map nucleosomes as well as other DNA-binding proteins such as transcription factors.
Benjamin R Carone