Dataset features

Specifications


Dataset type: Other
Number of samples: 5
Release date: Apr 3 2018
Last update date: Jul 18 2018
Access: Public
Taxon: Homo sapiens
Dataset link Divergence in DNA specificity among paralogous transcription factors contributes to their differential in vivo binding [RG_E2F1-3-4_cust2_v1]

Experimental Protocol


Five genomic-context protein binding microarray (gcPBM) experiments were performed for recombinant, full-length, human transcription factors E2f1, E2f3, and E2f4. Briefly, the PBMs involved binding of GST-tagged transcription factors E2f1, E2f3, and E2f4 to double-stranded 180K Agilent microarrays in order to determine their binding specificity for putative DNA binding sites in native genomic context. Each genomic DNA sequence represented on the array is present in 6 replicate spots. We report the gcPBM signal intensity for each spot.

Repositories


GEO

GSE97886

BioProject

PRJNA383141

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Contact


Raluca Gordan