Dataset features

Specifications


Application: DNA methylation array analysis
Number of samples: 51
Release date: Dec 31 2012
Last update date: Jan 2 2015
Access: Public
Diseases: Ovarian Diseases, Tumor Lysis Syndrome, Neoplasms, Second Primary, Cystadenoma, Serous
Dataset link The DNA methylomes of serous borderline tumours reveal subgroups with malignant-like or benign-like profiles

Experimental Protocol


Array-based methylation profiling was performed using the Infinium HumanMethylation27 BeadChip in 12 low grade serous carcinoma, 19 serous borderline tumours and 16 benign serous tumours. The reproducibility of the Infinium HumanMethylation27 BeadChips was evaluated using four biological replicates of the high grade serous ovarian cancer cell line PEO1. Differential methylation cutoff was estimated from four biological replicates by bootstrap resampling and set at Δβ ≥ 0.25 corresponding to a FDR ≤ 0.09.

Repositories


GEO

GSE40105

ArrayExpress

E-GEOD-40105

BioProject

PRJNA172841

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Contact


Wei Dai