Dataset features

Specifications


Application: RNA-seq analysis
Number of samples: 90
Release date: Dec 1 2016
Last update date: Nov 21 2018
Access: Public
Diseases: Huntington Disease, Tooth Loss
Dataset link Transcriptional profiling of cortex and striatal tissue following chronic dosing of PDE10A inhibitor PF-02545920 in a Q175 homozygous knock-in mouse model of Huntington’s disease

Experimental Protocol


Transcriptional profiling of cortex and striatal tissue following chronic dosing of either vehicle or the  PDE10A inhibitor PF-02545920 (0.32, 1 and 3.2 mg/kg po qd) in the Q175 homozygous knock-in mouse model of Huntington’s disease (dosing from 5-weeks to 9 months of age).

Repositories


GEO

GSE89505

ENA

SRP092552

BioProject

PRJNA352400

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Contact


Jeff Aaronson