Computational protocol: Manual Khalifa Therapy Improves Functional and Morphological Outcome of Patients with Anterior Cruciate Ligament Rupture in the Knee: A Randomized Controlled Trial

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Protocol publication

[…] When this study was performed, Khalifa therapy had never been evaluated before. Because of the extraordinary success rates in anecdotal reports after this therapy and assuming a clinically large intergroup effect size, we deemed 15 patients per group sufficient to determine effects of the therapy for this study.Data preparation was performed using Microsoft Excel 2007. For data analysis, IBM SPSS 16 and Statistica Version 8 were used. Kolmogoroff-Smirnov Test and graphical analyses were used for evaluation of normal distribution. Continuous data was analysed by repeated measure analysis of variance, rank order data was analysed using Wilcoxon signed rank test for changes and Mann-Whitney-U test for between group differences. For the frequency between 2 groups, the Fisher exact test was used for paired groups and the chi-square test for unpaired groups with Yates' correction for small cell frequencies. Interobserver reliability of MRI grading was assessed using the Kappa statistic. The level of significance was set at P ≤ 0.05. Analysis was performed as intention to treat. […]

Pipeline specifications

Software tools SPSS, Statistica
Applications Miscellaneous, Magnetic resonance imaging
Organisms Homo sapiens
Diseases Musculoskeletal Diseases, Rupture