Dataset features

Specifications


Application: RNA-seq analysis
Number of samples: 24
Release date: Jan 24 2017
Last update date: Oct 18 2018
Access: Public
Diseases: Leukemia
Chemicals: Zinc
Dataset link The MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in MLLr AML

Experimental Protocol


Genome-wide (ChIP-seq) binding of MLL, AF9, AF4, H3K4me3, H3K27ac, H3K79me2 and RUNX1 in THP-1 and MV4-11 AML cell lines. Expression Profiling (RNA-seq) of THP-1 and MV4-11 cell lines, as well as 5 MLL-AF9 positive patient blasts.

Repositories


GEO

GSE79899

ENA

SRP072835

BioProject

PRJNA317349

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