Dataset features

Specifications


Application: DNA methylation array analysis
Number of samples: 49
Release date: Sep 17 2017
Last update date: Nov 27 2018
Access: Public
Diseases: Autoimmune Diseases, Cardiovascular Diseases, Encephalitis, Arbovirus, Metabolic Diseases, Multiple Sclerosis
Dataset link Epigenomic and lipidomic changes in Multiple Sclerosis patients with high Body Mass Index enhance the neurotoxic function of monocytes

Experimental Protocol


23 Multiple Sclerosis patients with high Body Mass Index (25 and over) and 26 Multiple Sclerosis patients with low Body Mass Index (under 25) were recruited for the study. Monocytes were isolated from the blood of patients using CD14 beads and DNA extracted and bisulfite converted from the sorted cells. Genome-wide DNA methylation levels were assessed using Illumina Infinium HumanMethylation450 BeadChip.

Repositories


GEO

GSE103929

BioProject

PRJNA407633

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Contact


Patrizia Casaccia