Global changes of gene expression inuced by MIR31HG knockdown

Human adipose-derived stem cells (hASCs) are a highly attractive source in bone tissue engineering.We found that MIR31HG significantly promote the osteogenic differentiation of hASCs. However, the underlying mechanisms still await investigations. Thus the alteration of gene expression induced by MIR31HG knockdown was investigated. We used microarrays to detail the global programme of gene expression when MIR31HG was knocked down in hASCs and identified distinct classes of dn-regulated genes during this process.

Dataset features

Information

Specifications

Application:	Gene expression microarray analysis
Number of samples:	4
Release date:	Oct 7 2018
Last update date:	Oct 8 2018
Access:	Public
Dataset link	Global changes of gene expression inuced by MIR31HG knockdown

Experimental Protocol

hASCs were transfected with shMIR31HG or the control vectors (shNC). Total RNA was isolated with Trizol from hASCs.

Repositories

GEO

GSE73919

BioProject

PRJNA298538

Download

Contact

Lingfei Jia