Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 136
Release date: Apr 10 2009
Last update date: Oct 29 2018
Access: Public
Diseases: Lymphoma, Neoplasms, Lymphoma, B-Cell
Computational protocol: Primer3, Mutation Surveyor, dbSNP
Dataset link Mutations of multiple genes deregulate the NF-kB pathway in diffuse large B cell lymphoma

Experimental Protocol


DLBCL biopsies from 73 patients were collected from the archives of the Departments of Pathology at Columbia University and Weill Cornell Medical College. Total RNA was extracted from frozen tumor biopsies and processed according to Affymetrix standard protocols. Purified tonsillar geminal center, naive and memory B cells (5 samples each from different individuals) were purified by magnetic cell separation as described in Klein et al, PNAS 2003. The dataset includes also: 38 Follicular lymphoma biopsies and 5 lymphoblastoid cell lines.

Repositories


GEO

GSE12195

ArrayExpress

E-GEOD-12195

BioProject

PRJNA113415

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Contact


Laura Pasqualucci

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