Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 27
Release date: Apr 8 2016
Last update date: Aug 13 2018
Access: Public
Diseases: Melanoma, Neoplasms
Dataset link The aging microenvironment promotes melanoma cell invasion and therapy resistance

Experimental Protocol


To assess the effects of the aging microenvironment on melanoma cell gene expression, we co-cultured dermal fibroblasts from young (55 years) individuals with three different melanoma cell lines (UACC1273, M93-047 and UACC903) in triplicate using transwell chambers. After 96 h of co-culture, fibroblasts in the upper well were removed, and melanoma cells (lower chamber) were subjected to microarray analysis.

Repositories


GEO

GSE57445

BioProject

PRJNA246469

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Contact


Kevin Becker

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