Dataset features

Specifications


Application: DNA methylation array analysis
Number of samples: 32
Release date: Feb 18 2015
Last update date: Feb 20 2015
Access: Public
Chemicals: Diethylhexyl Phthalate
Dataset link DNA methylation changes in fetal germ cells exposed to endocrine disruptors and in the next generation [methylation set 1]

Experimental Protocol


Pregnant mice were gavaged daily with endocrine distruptors (VZ at 100 mg/kg/day, DEHP at 750 mg/kg/day, BPA at 0.2 mg/kg/day or control oil) starting at 12.5 days post coitum (dpc) and the G1R germ cells were purified from the exposed fetuses at 17.5 dpc. The G2R germ cells were purified from fetuses that were sired by males that had been treated in utero in a G0 mother. G1R spermatozoa were collected from adult males that had been treated in utero at the fetal stages. G2R spermatozoa were collected from adult males who were sired by in-uteo-treated males.

Repositories


GEO

GSE59539

ArrayExpress

E-GEOD-59539

BioProject

PRJNA255526

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Contact


Piroska Szabo
Piroska E Szabo