|Application:||SNP array data analysis|
|Number of samples:||2|
|Release date:||Mar 23 2017|
|Last update date:||Jul 13 2018|
|Taxon:||Homo sapiens, Cucumber necrosis virus|
|Dataset link||Comprehensive performance comparison of high-resolution array platforms for genome-wide Copy Number Variation (CNV) analysis in humans [AffymetrixCytoScanHD]|
We systematically compared the genome-wide CNV detection power of all 17 available array designs from the Affymetrix, Agilent, and Illumina platforms by hybridizing the well-characterized genome of 1000 Genomes Project subject NA12878 to all arrays in two technical replicates, and performing data analysis using both manufacturer-recommended and platform-independent software. We benchmarked the resulting CNV call sets from each array using a gold standard set of CNVs for this genome derived from 1000 Genomes Project whole genome sequencing data.