|Application:||Gene expression microarray analysis, miRNA array analysis|
|Number of samples:||16|
|Release date:||May 6 2009|
|Last update date:||Apr 5 2017|
|Dataset link||Expression profile analysis of inflammatory response regulated by hepatocyte nuclear factor 4α|
The different treated HepG2 cells were grouped into 4 groups (four replicates in each group): Group1, Control; Group2, HNF-4α shRNA treated cells; Group3, cytokine treated group; Group4, HNF-4α shRNA and cytokine treatments. RNA extraction and hybridization on Affymetrix microarrays were processed. The expression profiles between different groups were analyzed and compared. In order to explore the function of HNF-4α in the inflammatory response, a set of 170 genes annotated as inflammatory response was obtained from GO (geneotology.org), the enrichments of these inflammatory genes were analyzed in different treated groups.