Dataset features

Specifications


Dataset type: Expression profiling by array, RNAi profiling by array, Transcriptome or Gene expression
Number of samples: 16
Release date: May 6 2009
Last update date: Apr 5 2017
Access: Public
Genes: HNF4A
Dataset link Expression profile analysis of inflammatory response regulated by hepatocyte nuclear factor 4α

Experimental Protocol


The different treated HepG2 cells were grouped into 4 groups (four replicates in each group): Group1, Control; Group2, HNF-4α shRNA treated cells; Group3, cytokine treated group; Group4, HNF-4α shRNA and cytokine treatments. RNA extraction and hybridization on Affymetrix microarrays were processed. The expression profiles between different groups were analyzed and compared. In order to explore the function of HNF-4α in the inflammatory response, a set of 170 genes annotated as inflammatory response was obtained from GO (geneotology.org), the enrichments of these inflammatory genes were analyzed in different treated groups.

Repositories


GEO

GSE15991

ArrayExpress

E-GEOD-15991

BioProject

PRJNA115349

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Contact


Peter Burke