Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 10
Release date: Mar 28 2014
Last update date: May 15 2017
Access: Public
Diseases: Leukemia, Leukemia, Megakaryoblastic, Acute, Neoplasms
Genes: MIR99A, TGFB1, APC2, CTNNB1, KAS I and II
Dataset link miR-99a/100~125b tricistrons regulate hematopoietic stem and progenitor cell homeostasis by shifting the balance between TGFβ and Wnt signaling

Experimental Protocol


We lentivirally transduced cord blood CD34+-hematopoietic stem and progenitor cells (CB-HSPCs) to ectopically express miR-125b-2, miR-99a, let-7c or miR-99a~125b-2 and cultured them in megakaryocytic differentiation medium for 7 days.

Repositories


GEO

GSE56335

ArrayExpress

E-GEOD-56335

BioProject

PRJNA242939

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Contact


Jan-Henning Klusmann