Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 112
Release date: Feb 10 2017
Last update date: Oct 29 2018
Access: Public
Diseases: Leukemia, Leukemia, Hairy Cell, Leukemia, Myeloid, Acute, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Follicular
Chemicals: Cholesterol
Dataset link Expression data from 12 BPDCN samples, 35 T-ALL samples, and 65 AML samples

Experimental Protocol


Leukemic samples were obtained from patients at diagnosis, with acute leukemia through bone marrow aspirates or blood collection, for RNA extraction and hybridization on Affymetrix microarrays. Acute leukemia were classified according to the standard morphological and immunophenotypic and/or immunohistochemical World Health Organization (WHO) criteria. AML samples were sub-categorised following French-American-British (FAB) classification. T-ALL were sub-categorised as described (Asnafi et al., Blood 2003). The 12 BPDCN were obtained from our national network (authorization number DC-2008-713). Diagnosis was established BPDCN based on histopathology and immunostaining of cutaneous lesions, as described previously (Garnach-Ottou et al., Br J Haematol., 2009; Angelot-Delettre et al., Cytometry A., 2012; Riaz et al., Cancer Control., 2014).

Repositories


GEO

GSE89565

BioProject

PRJNA352564

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Contact


frédéric leprêtre