Dataset features

Specifications


Application: RNA-seq analysis
Number of samples: 36
Release date: Aug 6 2018
Last update date: Nov 19 2018
Access: Public
Diseases: Deficiency Diseases, Influenza, Human, Metabolism, Inborn Errors, Pneumonia, Respiratory Syncytial Virus Infections
Dataset link Life-threatening influenza pneumonitis in a child with inherited IRF9 deficiency

Experimental Protocol


Total of 72 samples, 38 samples from primary fibroblasts and 34 samples from EBV-transformed B cells, were analyzed using paired-end RNA sequence data. Out of 38 samples from primary fibroblasts, 3 control samples are paired with no stimulation vs IFNa2b stimulation. Out of 34 samples from B-cells, 3 control samples are paired with no stimuliion vs IFNa2b stimulation. In addition to healthy control subjects, patients with AR complete STAT1 (STAT1 -/-) or STAT2 (STAT2 -/-) deficiency were analyzed for comparison.

Repositories


GEO

GSE117637

ENA

SRP155182

BioProject

PRJNA482784

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