Dataset features

Specifications

Application:	Gene expression microarray analysis
Number of samples:	6
Release date:	Dec 3 2010
Last update date:	Aug 23 2018
Access:	Public
Diseases:	Cardiovascular Diseases, Heart Failure
Dataset link	Cardiac gene expression profiling of heart failure treatment with the anti-ischemic drug ranolazine

Experimental Protocol

Microarray gene expression profiling was performed with heart tissue isolated from three study groups: (i) untreated 10 month-old C57BL/6J (B6) mice with heart failure induced by 6 months of abdominal aortic constriction (AAC), (ii) 10 month-old B6 mice with 6 months of AAC and two months of treatment with the anti-ischemic drug ranolazine (200 mg/kg), and (iii) age-matched, untreated, sham-operated B6 control mice.