Computational protocol: Correlation between the Effects of Acupuncture at Taichong (LR3) and Functional Brain Areas: A Resting-State FunctionalMagnetic Resonance Imaging Study Using True versus Sham Acupuncture

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Protocol publication

[…] Preprocessing was carried out using Data Processing Assistant for Resting-State fMRI (DPARSF; Chao-Gan and Yu-Feng, 2010, http://www.restfMRI.net), which is based on Statistical Parametric Mapping (SPM8; http://www.fil.ion.ucl.ac.uk/spm/) and Resting-State fMRI Data Analysis Toolkit (REST, Song et al., 2011. http://www.restfMRI.net) [, ]. This includes DICOM format conversion, removal of 10 time points before image scanning, time correction, correction of head movement, space standardization, and space smoothing. After preprocessing, 15 subjects were included in the statistical analysis. ReHo analysis: using REST1.8 software, linear tendency of the data after preprocessing (space standardization was completed, and space smoothing was not finished) was removed by linear regression. Time and curve were convolved using Hamming bandpass filtering. ALFF was extracted (0.01–0.08 Hz). Kendall's coefficient of concordance of each subject was computed, so each subject had a Kendall coefficient of concordance map, that is, ReHo map. This map was divided by the mean of the whole brain, and standardized ReHo was obtained and used in statistical analysis [, , ]. ALFF analysis: using REST1.8 software, linear tendency of the data after preprocessing (space smoothing was completed) was removed by linear regression. Time and curve were convolved using Hamming bandpass filtering. ALFF was obtained (0.01–0.08 Hz). ALFF of each subject was computed, so ALFF maps were obtained. ALFF value was divided by the mean of the whole brain, and standardized ALFF was obtained []. ReHo analysis: using REST1.8 software, linear tendency of the data after preprocessing (space standardization was completed, and space smoothing was not finished) was removed by linear regression. Time and curve were convolved using Hamming bandpass filtering. ALFF was extracted (0.01–0.08 Hz). Kendall's coefficient of concordance of each subject was computed, so each subject had a Kendall coefficient of concordance map, that is, ReHo map. This map was divided by the mean of the whole brain, and standardized ReHo was obtained and used in statistical analysis [, , ].ALFF analysis: using REST1.8 software, linear tendency of the data after preprocessing (space smoothing was completed) was removed by linear regression. Time and curve were convolved using Hamming bandpass filtering. ALFF was obtained (0.01–0.08 Hz). ALFF of each subject was computed, so ALFF maps were obtained. ALFF value was divided by the mean of the whole brain, and standardized ALFF was obtained []. […]

Pipeline specifications

Software tools DPABI, SPM, REST
Application Functional magnetic resonance imaging
Diseases Pain Insensitivity, Congenital