Dataset features

Specifications


Application: RNA-seq analysis
Number of samples: 24
Release date: Feb 28 2017
Last update date: Nov 28 2018
Access: Public
Diseases: Breast Neoplasms, Neoplasms
Genes: DNER, BRD2, BRD3, BRD4, BRDT, MCL1
Dataset link Global transcriptome profiling of triple-negative breast cancer cell lines treated with small-molecules targeting Bromodomain and Extra Terminal (BET) proteins

Experimental Protocol


Global gene transcription profiling was performed in MDA-MB-157, MDA-MB-231 and MDA-MB-468 cell lines treated with DMSO, Thalidomide (1000 nmol/L), BETi-211 (1000 nmol/L) or BETd-246 (100 nmol/L) for 3 hours. Independent biological replicates (such as DMSO1 and DMSO2) were analyzed for each cell line under each condition. Both DMSO- and Thalidomide-treated samples were used as controls.

Repositories


GEO

GSE95375

ENA

SRP100726

BioProject

PRJNA376804

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Contact


Shaomeng Wang