Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 62
Release date: Oct 31 2015
Last update date: Oct 22 2018
Access: Public
Diseases: Breast Neoplasms
Dataset link Gene expression profiling in response to radiation treatment in human breast cancer

Experimental Protocol


Women 55 or older with clinically node negative, ER+ and/or PR+, HER2-, T1 invasive carcinomas or low-intermediate grade in situ disease ≤2cm were enrolled (n=32). Intensity-modulated radiotherapy was used to deliver 15 Gy (n=8, patients 01-08), 18 Gy (n=8, patients 09-16), or 21Gy (n=16, patients 17-32) to the tumor with a 1.5cm margin. Lumpectomy was performed within 10 days. Paired pre- and post-radiation MRI images and patient tumor samples were analyzed.

Repositories


GEO

GSE65505

ArrayExpress

E-GEOD-65505

BioProject

PRJNA274283

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