Dataset features

Specifications


Application: DNA methylation array analysis
Number of samples: 24
Release date: Mar 8 2016
Last update date: Jul 25 2018
Access: Public
Diseases: Diabetic Neuropathies
Chemicals: Glucose
Dataset link Altered DNA methylation of glycolytic and lipogenic genes in liver from obese and type 2 diabetic patients [methylome analysis]

Experimental Protocol


To better understand the molecular mechanisms underlying the development of hepatic insulin resistance and type 2 diabetes at a molecular level, we performed a genome-wide methylome and transcriptome analysis of liver from non-obese metabolically healthy, obese non-diabetic and obese type 2 diabetic patients. Distinct DNA methylation and gene expression profiles were identified in liver from the obese and type 2 diabetic patients compared with the non-obese participants.

Repositories


GEO

GSE65057

BioProject

PRJNA272810

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