|Application:||DNA methylation array analysis|
|Number of samples:||7|
|Release date:||May 23 2017|
|Last update date:||Nov 27 2018|
|Dataset link||Genomic and molecular screenings unveil different mechanisms for acquired resistance to MET inhibitors in lung cancer cells|
The EBC1 cells, which are sensitive to TKIs against MET, were used to generate multiple clones with AR to a MET-TKI. Whole exome sequencing, RNA sequencing and global DNA methylation analysis were used to scrutinize the genetic and molecular characteristics of the resistant cells.