Dataset features

Specifications


Application: DNA methylation array analysis
Number of samples: 7
Release date: May 23 2017
Last update date: Nov 27 2018
Access: Public
Diseases: Lung Neoplasms
Chemicals: Tyrosine
Dataset link Genomic and molecular screenings unveil different mechanisms for acquired resistance to MET inhibitors in lung cancer cells

Experimental Protocol


The EBC1 cells, which are sensitive to TKIs against MET, were used to generate multiple clones with AR to a MET-TKI. Whole exome sequencing, RNA sequencing and global DNA methylation analysis were used to scrutinize the genetic and molecular characteristics of the resistant cells.

Repositories


GEO

GSE92608

BioProject

PRJNA358149

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