Computational protocol: Influence of region-of-interest designs on quantitative measurement of multimodal imaging of MR non-enhancing gliomas

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Protocol publication

[…] All patients were studied using a 3.0-T MRI scanner (Signa HDxt or DiscoveryMR 750; GE Medical Systems, Milwaukee, WI, USA) within a week before the operation. T1-weighted imaging with gadolinium enhancement was used to select patients with non-enhancing gliomas. T2-weighted (T2) or FLAIR images were acquired in all cases for delineation of tumors. DTI was acquired using a single-shot echo-planar imaging technique with TE=80 and TR=10,000. Diffusion gradient encoding in 25 directions with b=2,000 s/mm2 and an additional measurement without the diffusion gradient (b=0 s/mm2) were performed (). A parallel imaging technique was used to record data with a 128×128 spatial resolution for a 260×260 mm field of view. A total of 50 sections were obtained, with a section thickness of 3 mm and no intersection gap. ADC and FA maps were processed using Diffusion Toolkit (Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA; http://www.trackvis.org/dtk/). […]

Pipeline specifications

Software tools DTK, TrackVis
Applications Magnetic resonance imaging, Diffusion magnetic resonance imaging analysis
Organisms Homo sapiens
Diseases Glioma, Neoplasms
Chemicals Fluorodeoxyglucose F18