Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 15
Release date: Jun 14 2017
Last update date: Nov 9 2017
Access: Public
Diseases: Leukemia, Myeloid, Acute
Dataset link Effect on bone marrow mesenchymal stromal cells of mouse models of acute myeloid leukemia of different genotypes

Experimental Protocol


We established syngeneic AML, produced by different known AML fusion oncogenes, in C57BL/6 mice and isolated their BM-MSC. Gene expression profiling was used to compare AML-exposed MSC to those of control mice. BM-derived normal MSC were also cultured in vitro with tp53 WT and tp53-/- AML cells of the same genotype (MLL/ENL+FLT3-ITD).

Repositories


GEO

GSE97194

BioProject

PRJNA380934

Download


Contact


Zhiqiang Wang