Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 8
Release date: Sep 1 2016
Last update date: Jan 9 2018
Access: Public
Chemicals: Estrogens
Genes: TERF2, XRCC3, SLX4, MAPK3
Dataset link The cellular response of immortalized TRF2dB fibroblast cells by 4-hydroxytamoxifen drug treatments

Experimental Protocol


Cellular response in immortalized human fibroblast transduced with ERT2-TRF2dB gene was measured at 0, 12, 24, 36, 48 and 60 hours of 1 µM 4-hydroxytamoxifen (4-OHT). IFNb gene expression in immortalized human fibroblast transduced with vector was measured at 0 and 48 hrs of 1 µM 4-hydroxytamoxifen (4-OHT) as controls. Cellular expression of treated ERT2-TRF2dB cells are normalized to untreated ERT2-TRF2dB cells and compared to the expressions of 4-OHT treated vector fibroblast cells that are normalized to untreated vector fibroblast cells. Three independent experiments were performed at each time for each experiment. Liuh-Yow, Chen

Repositories


GEO

GSE86274

BioProject

PRJNA341341

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Contact


Liuh-Yow Chen