Computational protocol: Novel mutations in TLR genes cause hyporesponsiveness to Mycobacterium avium subsp. paratuberculosis infection

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Protocol publication

[…] The ovine TLR nucleotide sequences obtained in this study were aligned by ClustalW multiple alignment method (DNASTAR software), translated into putative amino acids and consensus sequences were obtained (BioEdit software). LRR motifs were outlined according to the method described earlier [] using PFAM and SSpro4.0 servers []. […]

Pipeline specifications

Software tools Clustal W, BioEdit, SSpro
Databases Pfam
Application Protein structure analysis
Organisms Mycobacterium avium
Diseases Infection, Paratuberculosis, Mycobacterium avium-intracellulare Infection