Computational protocol: Dynamic Regulation of Tgf-B Signaling by Tif1γ: A ComputationalApproach

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Protocol publication

[…] The model consists of a system of nonlinear, ordinary differential equations that merge the ODE models of receptor trafficking and Smad shuttling . Briefly, the receptors described in the Smad shuttling model were replaced by those of the receptor trafficking model using unit conversion in a cell volume of 2.27×10−12L. Model building, parameters, system ordinary equations and description of the model in Systems Biology Markup Language (SBML) are detailed in and and . Model simulations were implemented with the mathematical Scipy library of Python language programming and the Matplotlib Python 2D plotting library was used to visualize the simulation curves. […]

Pipeline specifications

Software tools SciPy, matplotlib
Applications Miscellaneous, WGS analysis