|Number of samples:||2|
|Release date:||May 4 2016|
|Last update date:||Jul 20 2018|
|Dataset link||TET2 Regulates Mast Cell Differentiation and Proliferation through Catalytic and Non-catalytic Activities.|
Genomic DNA of FACS-sorted Kit+ FcεRIα+ populations of primary bone marrow-derived mast cells (BMMCs) from Tet2-/- and Tet2+/+ animals was extracted. Changes in 5hmC deposition were assessed genome-wide by biotin-based enrichment of 5hmC (Hydroxymethylation Collector-seq Kit, Active Motif) and multiparallel sequencing.