Computational protocol: Comparison of Clinical Effects between Percutaneous Transluminal Septal Myocardial Ablation and Modified Morrow Septal Myectomy on Patients with Hypertrophic Cardiomyopathy

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Protocol publication

[…] Standard cardiopulmonary bypass and myocardial preservation techniques were used. After aortotomy, the resection was started by making two parallel longitudinal incisions in the septum, the first beneath the nadir of the right coronary cusp and the second beneath the commissure between the right and the left coronary cusps. The classic incision was extended with a midventricular resection, beginning with continued resection leftward toward the mitral valve annulus and apically to the bases of the papillary muscles. All areas of papillary muscle fusion to the septum or ventricular free wall were divided, and anomalous chordal structures, muscle bundles, and fibrous attachments of the mitral leaflets to the ventricular septum or free wall were divided or excised.[]PTSMA was usually selected in elderly patients who have a high risk of surgical therapy. When patients need receive valvular surgery or coronary artery bypass operation, they were excluded from the study. All patients gave informed consent before these respective procedures. […]

Pipeline specifications

Software tools EMBOSS, MUSCLE
Application Nucleotide sequence alignment
Organisms Homo sapiens, Martes pennanti
Diseases Cardiomyopathy, Hypertrophic, Ventricular Septal Rupture