|Number of samples:||8|
|Release date:||Aug 22 2016|
|Last update date:||Oct 24 2018|
|Dataset link||Reprogramming by de-bookmarking somatic transcriptional program via targeting the BET bromodomains|
human BJ cells were treated with JQ1 at 50 nM for 48 hours. Differential expression was compared with DMSO treatment. The same treatments and comparsion were conducted for reprogramming BJ cells, which were transduced with OCT4, SOX2, and KLF4. JQ1iPSC5 is a iPSC (induced pluripotent stem cell) line generated in this study using small molecules JQ1.