Computational protocol: Effect of orlistat on periostin, adiponectin, inflammatory markers and ultrasound grades of fatty liver in obese NAFLD patients

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Protocol publication

[…] Descriptive statistics were used to analyze the demographic and clinical characteristics of the patients. Data were expressed as mean (SD) or median value (interquartile range). Kolmogorov–Smirnov and Shapiro–Wilk tests were carried out to identify normally distributed variables. Independent sample t-tests were used for between-group comparisons at baseline. Paired t-tests were used to evaluate within-treatment changes between baseline and the end of treatment, whereas between-treatment changes at the end of treatment were tested using one-way analysis of covariance with the initial value as a covariate. The Wilcoxon signed-rank test, or the Mann–Whitney U test, was used if nonparametric tests were required. Variables were correlated with Spearman’s rho correlation analysis. The significance level was set at P-value <0.05. Data were analyzed using a statistical software SPSS, version 21.0 (SPSS, Inc., Chicago, IL, USA). The sample size was calculated using a software G*Power version 3.1 (Heinrich-Heine-Universität, Düsseldorf, Germany). […]

Pipeline specifications

Software tools SPSS, G*Power
Application Miscellaneous
Organisms Homo sapiens
Diseases Fatty Liver, Neoplasms, Non-alcoholic Fatty Liver Disease